In pursuit of the secrets of the microbiota

That sounds interesting. I'm sure this will speak to all those people who change their diets at the slightest fad dictated by our dear media...; ))) I am not a doctor, but what I deduce is that any excess is harmful: Eat NATURALLY and EVERYTHING! 

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The intestinal microbial flora, or microbiota, which lines our intestines represents approximately 100 billion bacteria. More and more researchers are devoting themselves to the study of these microorganisms, which are suspected to play an important role in the health of their host. Recently, research work has shown that these bacteria can be divided, in humans, into three distinct enterotypes independent of traits such as age, sex, ethnic origin or body mass index.

This time, researchers from the University of North Carolina found that one type of intestinal cell, colonocytes, only survives on the energy provided by a cost-chain fatty acid, butyrate, which is the product of the breakdown of indigestible carbohydrates by the microbiota. Thus in “germ-free” mice, these cells manage to survive solely by digesting some of their own components, a process known as autophagy.

The addition of butyrate made it possible to stop this process of autophagy. This new insight into the role of butyrate may also have clinical and dietary implications, the researchers point out. “Dietary factors known as prebiotics promote the growth of some bacteria at the expense of others and have implications for human health and disease,” they write. " When our diet changed from a diet high in fiber and complex carbohydrates to simple carbohydrates, the incidence of colorectal cancer and inflammatory bowel diseases such as rectocolitis or Crohn's disease increased.. It is possible that increasing the level of butyrate may help reverse this trend. »

Early clinical trials have shown improvement in inflammation associated with rectocolitis in mice and humans.

JI

source: Science & Avenir.fr


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